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How melanoma can resist newly approved drug combo therapy
Description: Researchers have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage. The research team found that the melanoma cells resist the combo therapy of BRAF+MEK inhibitors by developing highly unusual genetic changes in certain key cancer genes. These changes not only mark the presence of drug resistance melanoma cells but also tell us about potential new ways to shut them off. [Source: ScienceDaily]
URL: http://www.sciencedaily.com/releases/2015/01/150115122009.htm
Availability: Full Text
Source: ScienceDaily
Publish Date: 1/15/2015
Reading Level: Basic
Page Length:  

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