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Skin cancer has high incidence in the United States and is mainly caused by ultraviolet B (UVB) radiation. In this study, scientists demonstrated the role of 1,1-bis(3′-indolyl)-1-(p-chlorophenyl) methane (DIM-D) in the prevention of skin photocarcinogenesis using an in vivo UVB-induced skin cancer model. They also evaluated the efficiency of oleic acid-modified nanostructured lipid carriers to deliver DIM-D across the skin barrier into the epidermis for chemopreventive activity. [Source: Journal of Biomedical Nanotechnology]
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